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Furthermore, the levels of IS and p-CS increased as CKD progressed, reflecting the extent of kidney damage
In lung cancer cells, the disruption of iron metabolism is characterized by upregulation of iron transport proteins such as transferrin (Tf) and hepcidin, while the expression of ferroportin, an iron export protein, is reduced ( Figure 1 )

Upon hormone binding the fold of the ligand binding domain results in a globular structure with an interaction surface for binding of interacting proteins like co-activators (AF2) [Figure 10B]

doi: 10.1167/iovs.03-0689
