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Gastroenterology, 159 (3), 10851094

On the one hand, high expression of EC-SOD inhibited the increase in methylase activity and downregulated the expression of recombinant DNA methyltransferase 1(DNMT1) and DNMT-3b, thereby inhibiting the increase in HIF1 and biological oxidants

doi: 10.1016/j.jcm.2016.04.016

This precise targeting allows stubborn pigmentation to fade evenly and naturally over time
