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Antioxid Redox Signal 24:376391
The use of NAC as a chelator of heavy metals appears to be a promising area of medical research and further clinical studies to verify these preliminary findings are warranted
Based on this, in the subsequent I/R- and TMT-induced myocardial injury model, the drug not only enhanced GSH levels and GPX and GST activities to lower oxidative damage but also reduced TMT-induced pyroptosis and I/R-mediated apoptosis [205207]
This dual behavior is influenced by factors such as dose, environmental conditions, and the presence of metal ions
