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Sci Rep 16 , 9202 (2026)
Y., Choi, J

Liver dysfunction can disrupt this balance, leading to systemic effects and exacerbating liver pathology[64-66]

Its core lies in leveraging highly expressed specific receptors on BBB endothelial cells to trigger energy-dependent active transport by ligand-receptor recognition, thus overcoming the constraints of an intact BBB (Figure 4B)
