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Description
FMOs in the liver metabolize TMA into TMAO once it is taken into the bloodstream
This inefficient process produces excessive lactic acid, alters cellular pH, and causes microscopic muscle damage that can take days or weeks to repair
Chen, B
Based on the American Association of Poison Control Centers National Poison Data System, ~ 7,750 exposures to VPA including 119 severe and 2 fatal cases were reported in 2019 [2]
