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Description
Modulation of Transforming Growth Factor-Beta (TGF-Beta) Signaling by Endogenous Sphingolipid Mediators

conducted a systematic review and meta-analysis, comprising a total sample size of 1610 participants, to evaluate the efficacy and safety of anti-inflammatory agents in the treatment of MDD [127]

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Studies have shown that TGF-1 suppresses GCL expression via the JNKATF3 pathway, leading to GSH depletion and enhanced oxidative stress through increased protein and lipid peroxidation [121]
