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10.1016/j.dyepig.2025.113014 19 LongZ

Clinical trials study young, healthy volunteers taking a single medication in a controlled setting
Symptoms include general symptoms of anemia (weakness, increased fatigue, difficulty concentrating, dizziness, rapid heart rate, shortness of breath, paleness) and symptoms from the digestive system, such as weight loss and loss of appetite, loss of taste, nausea, diarrhea, or constipation

However, we did find in ME/CFS raised lactate concentrations in both pgACC and dACC, and in long COVID, decreased concentrations of total choline in dACC, compared to healthy controls
