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Its primary mechanism is believed to pivot around enhancing lipolysis, the breakdown of fat, and suppressing lipogenesis, the process of fat accumulation [More et al., 2014]
Fickert P, Stieger B
This study also suggested that cancer stem cells display mesenchymal properties, including the upregulation of mesenchymal markers and the downregulation of epithelial markers
Grimwade and Leonard (2021) also presented a model showing how FIS participates in the regulation of initiation
