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The model showed midbrain cholesterol accumulation, enhanced triacylglycerol (TAG) hydrolysis, accompanied by DA neuron loss, astrogliosis, increased -syn expression, and significant elevation of lipid peroxidation and ferroptosis markers, correlating with motor deficits (Maniscalchi et al., 2024)

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doi:10.1152/japplphysiol.00141.2010 Baguet, A., Everaert, I., Hespel, P., Petrovic, M., Achten, E., & Derave, W
