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Description
Concurrently, excessive poly ADP-ribose (PAR) polymers generated by PARP-1 accumulate intracellularly, forming PAR signaling platforms that recruit pro-death factors like AIF [67]
Ons lichaam bestaat uit moleculen
Specifically, casein kinase 1 family members are reported to act on substrates via sequential phosphorylation of serine/threonine residues following a canonical pSxx(S/T) motif
P.MeisterA
