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Eur J Clin Invest 31:10071011
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Effect of Epitalon on Lifespan, Free Radical Processes, and Antioxidant Enzyme Activity. Experimental Gerontology
Cytotoxic Mechanisms of NQO1 Bioactivating Compounds As stated in previous sections, NQO1 acts as a double-edged sword by playing crucial roles in cellular defense against oxidative stress induction by preventing the generation of ROS and at the same time catalyzing futile reductive cycles with certain quinones, leading to heightened redox stress in cancer cells
