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Each study was assessed independently by RS and FS, and the included studies were categorized based on risk domains (Figure 2)

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Interestingly, ABHD5 mutations causative in CDS do not co-localize to LDs and are unable to stimulate PNPLA2 lipolytic activity (30), demonstrating an important function for the interaction in the etiology of CDS and lipid storage

Spread primarily by the body louse, typhus was the cause of an estimated 3 million deaths, especially during war and famine, in Poland and the Soviet Union from 1915 to 1922