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All the significance analysis was done using Statistica 8.0 software, using one-way ANOVA or two-tailed heteroscedastic Students t -test

Extracellular oxygen consumption rate and acidification assays The oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) were evaluated using the Seahorse XF Pro Analyzer (Agilent Technologies, Santa Clara, CA, USA), following the manufacturers protocols

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95% CI, 1.1511.04)
