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Description
A double dose of lamotrigine or valproic acid is required in patients co-treated with lopinavir/ritonavir owing to induction of UGT activity
Altogether, the major efforts in managing NF1-related neoplasms have been based on drugs targeting signaling transduction cascades such as RTK, RAS- RAFMEKERK and PI3K-AKTmTOR inhibitors
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Numerous case series have demonstrated its clinical efficacy when used either as a standalone treatment or in combination with oral immunotherapy (Quoc et al
