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Description
Intrathecal administration ensures that tofersen targets motor neurons with pinpoint accuracy through cerebrospinal fluid, effectively diminishing cerebrospinal levels of SOD1 protein and plasma levels of neurofilament light chainsbiomarkers that signal the regression of neuronal damage (43)

We can usually pinpoint the weekend on the calendar that explains the result

(PubMed) Berry MJ, Banu L, Harney JW, Larsen PR

Von Mehrens feels his life expectancy is definitely NOT 10 years and possibly not even 5