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A recent overview article summarizing AOD 9604 research notes that in isolated chondrocyte cultures, AOD 9604 has been reported to promote proteoglycan and collagen production , and may influence differentiation of adipose-derived mesenchymal stem cells toward osteogenic lineages suggesting a possible role as a tool to study cartilage and bone matrix biology

Category 2 includes substances that raise significant safety or efficacy concerns, meaning they generally cannot be used in compounding unless specific criteria are met

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The contents of other metabolites in feces were all lower than 0.06% of the administered amount, and it was impossible to perform structural identification because of the extremely low content