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doi: 10.1038/cddis.2013.447

Impacts of impaired mitochondrial dynamics in hearing loss: potential therapeutic targets

In response, this review highlights the current state of understanding of the nose-to-brain drug delivery pathway and how both biological and clinical barriers to drug transport using the pathway can been addressed, as illustrated by demonstrations of how currently approved intranasal sprays leverage these pathways to enable the design of successful therapies

How long does it take to notice changes with supplementation
