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Clinical evidence: The SURMOUNT-1 trial, published in the New England Journal of Medicine , showed that participants on the highest dose of tirzepatide (15 mg) lost an average of 22.5 percent of their body weight over 72 weeks the most weight loss ever demonstrated by a pharmaceutical agent in a clinical trial (Jastreboff et al., 2022)

Before beginning, the researchers measured the participants body weight and HbA1C results, an average blood sugar level to reflect the previous 23 months

Mobile electron carriers, like coenzyme Q (CoQ) and cytochrome c, move electrons between protein complexes

Gut 12 , 988994 (1971)