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Firstly, although we observed that the frequency and magnitude of Ca 2+ oscillation were more pronounced in cells from GCGR-KO mice, the detailed mechanism still needs to be elucidated

K., and Singhal M., Emerging Role of PlantBased Bioactive Compounds as Therapeutics in Parkinson's Disease, Molecules 28, no

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Therefore, a "link model" approach was used to implement the PK/PD model and to estimate the drug concentration in the effect-site compartment [24]