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The approved dose for TIS is 300 mg of antibiotic nebulised by a jet nebulizer twice a day every other month (Cheer et al., 2015), while for TIP the treatment consists in 112 mg (four 28 mg capsules) inhaled twice a day in alternating cycles of 28-day on/off treatment (Dring et al., Aztreonam Lysine Aztreonam is an antibiotic belonging to the family of monocyclic -lactams
The trial was delayed due to manufacturing problems
doi: 10.1016/j.brainres.2010.03.091, 46 KeeserD.MeindlT.BorJ.PalmU.PogarellO.MulertC.et al
adding niacin to the mix can increase the chances of this side effect even more
