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Clinical trials have been carried out on the effects of ALA on DPN, and its use for this condition is approved in many countries [22,89,90,91,92,93,94,95,96]
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However, this does not typically result in their death due to the capacity of Glu to synthesize glutathione (GSH), a vital antioxidant that plays a crucial role in cancer cells and their resistance to oxidative stress [45]
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