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Aldosterone, via the MR, amplifies kidney injury
GSS consists of three loops projecting from an antiparallel -sheet, a parallel -sheet and a lid of anti-parallel sheets, which provide access to the ATP-binding site
doi: 10.1152/ajpcell.1994.266.2.C367
In addition, superoxide reduces the bioavailability of NO and enhances superoxide production via uncoupled eNOS
