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Furthermore, moderate ROS activate pro-survival signaling pathways (PI3K/AKT, MAPK, and NF-B) as second messengers

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FIGURE 7 3.7 Molecular docking Molecular docking was performed on the top five target proteins (AKT1, INS, TNF, IL-6, and TP53) and five active components (Tridecanoic Acid, Pentadecanoic Acid, Hexadecanoic Acid, Adenosine Triphosphate, and Adenosine) from the PPI and SJZD-Active Components-Intersection Targets network with the highest Degree values