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Transport, turnover, and extracellular redox biology Glutamyl cycle and glutamyl transpeptidase (GGT): Extracellular GSH is hydrolyzed by GGT to glutamyl amino acids and cysteinylglycine, which are further processed and re-imported to support intracellular GSH resynthesis

doi: 10.1046/j.1365-201x.2000.00668.x

If persistent, extravascular hemolysis leads to a hyperplasia of phagocytes manifested by varying degrees of splenomegaly

These include viral envelope glycoproteins and bacterial toxins, as well as cellular factors that promote tumorigenesis 336
