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In agreement with these latter results, the work of Majors et al (1997) showed that a relatively low concentration of homocysteine (50 to 300 mol/L) stimulates collagen production in rabbit aortic smooth muscle cells that may favor extracellular matrix component accumulation in intimal lesions
The results showed that this treatment improved scar appearance compared to placebo [456458]
Intramuscular tissue is richly supplied with blood vessels so the medication is more rapidly absorbed by this route
