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Description
This essential vitamin aids in protein synthesis, fat and carbohydrate metabolism, and brain health

Ethylmalonic encephalopathy is characterized by encephalopathy, microangiopathy, chronic diarrhea, defective cytochrome c oxidase in muscle and brain, high concentrations of C4 and C5 acylcarnitines in blood (perhaps due to inhibition of short-chain acyl-CoA dehydrogenase by H 2 S), and high excretion of ethylmalonic acid in urine (Burlina et al

10.1016/j.medcli.2020.04.024 64

Philip Reigan for his help with molecular modeling and visualization of the ALDH protein in Figs