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Because the electrophilic carbon in these reactions is a methyl carbon, a stepwise S N 1-like mechanism is extremely unlikely: a methyl carbocation is very high in energy and thus is not a reasonable intermediate to propose
doi: 10.1134/S0006297918090079
Similar content being viewed by others Introduction Excitotoxicity plays a major role in neuronal degeneration associated with various neurodegenerative diseases such as Alzheimers disease (AD), Parkinsons disease (PD), amyotrophic lateral sclerosis (ALS), and epilepsy 1
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