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A multidisciplinary strategy is essential for effective ID-ADC development, integrating medicinal chemistry and bioinorganic techniques to create stable conjugations and build pathogen-responsive linkers (Kwon, 2021)

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5.2 Penetration of BBB One of the major hurdles in treating PD is overcoming the BBB, which can be efficiently achieved by surface modification of the NPs

Ammonia accumulation has a dual effect on autophagy (109, 110)