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The changes in cardiac work load from before to after pre-treatment were expressed in percentage of the load prior to pre-treatment, and that in response to tyramine as change from before to that after the 15-min infusion in percentage of the before value

doi:10.1056/NEJMoa2001180

There is no doubt that the molecular classifications have improved the prediction of the clinical outcome, and they provide key markers for a therapy tailored to the risk group

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