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In addition, T2D is the result of a complex interaction of environmental and genetic factors, being difficult to establish the role of each one in the pathogenesis of diabetes and in the levels of IGF-1

Based at least in part on the experimental results presented herein, a ratio of about 3:2 sodium: chloride (e.g., about 2.5:2, about 2.75:2, or about 3:2 sodium: chloride) may be important for maintaining membrane integrity and stability

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