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The control diet (D12450J) and HFD (D1249) for mice were purchased from Research Diets Inc

The efficacy of TMZ is intricately linked to the proper functioning of the MMR system, which explains why the downregulation of MLH1 can result in resistance to TMZ [161]

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Progressive vessel narrowing causes exertional ischemia (intermittent claudication) and chronic hypoperfusion signs like dermal atrophy, hair loss, and absent pulses
