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Description
The PEP-3 was proposed as an assessment tool to evaluate the treatment effects of the TEACCH

Mitochondrial reactive oxygen species (ROS) act as a key regulator, promoting RIPK1 autophosphorylation, which in turn enhances necrosome assembly and MLKL pore-forming capacity, ultimately driving necroptosis (32)

Nunn et al., 2020)
Long-term disc health requires ongoing attention to the factors that caused or contributed to the herniation in the first place
