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The Human Gene Mutation Database (HGMD) contains 43 different GSS variants that have been reported as of January 2023, with missense variants showing predominance (55.8%), followed by splice variants (21.0%), small insertions/deletions (11.5%), large insertions/deletions (7.0%), and nonsense variants (4.7%)

As we continue our quest for wellness, let us remember that our approach should be rooted in science and guided by our commitment to transparency and quality

Exclusion criteria included prior biologic therapy or documented history of PsA (ICD-10-CM code L40.5) before the index date

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