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3.1 Age-related macrostructural WM changes A variety of age-related macrostructural WM changes, including reduced WM volume, WM lesions, disrupted WM integrity, and subsequent cortical disconnection have all been observed in normal aging brains (Caligiuri et al., 2015)

To view a copy of this licence, visit About this article Cite this article Kongsui, R., Promsrisuk, T., Chanmanee, T

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