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Of the three haplotypes, the upstream genetic alterations that were in linkage disequilibrium with the Leu allele were also found to have the lowest level of activity in a transcription reporter gene assay, causing a 25% suppression in promoter activity (152)

2005;128(Pt 11):270512

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As such, regardless of the lifestyle and/or biological causes for Glutathione decline in each person, a decrease in levels can cause an increased susceptibility to many age-related conditions and diseases
