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D., Negative Regulation of TSC1TSC2 by Mammalian Dtype Cyclins, Cancer Research 65, no

In fibrotic lungs, lactate secreted by myofibroblasts induces H3K18 lactylation in macrophages, driving the expression of pro-fibrotic factors, including ARG1, PDGF-A, TSP-1, and VEGFA [103]

However, in diseases caused by complex pathogenic factors, antioxidant therapy is primarily approved to alleviate the toxic side effects of radiotherapy and chemotherapy or to be used as an adjunctive treatment rather than as a primary therapeutic approach

Jun 2000;52(6):263-7
