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As a positive control, treatment with 10 mM DEM did induce nuclear localization of DAF-16 (Figure 2figure supplement 2), consistent with this challenge inducing acute stress

In a phase-I/II trial, 12.7% of gefitinib-treated glioblastoma patients showed partial tumor regression

Since then, selenium deficiency has been studied as a common cause of thyroid disorders

doi: 10.1007/s11325-006-0074-x
