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Because GHK-Cu is researched for regenerative, tissue-remodeling, collagen-related, and cellular-signaling pathways, research involving active or suspected malignancies, copper-metabolism conditions, liver-related investigations, or complex dermatological research models may warrant additional monitoring and individualized evaluation

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Practical considerations for safety and consistency: Use a new sterile insulin syringe for every injection Rotate injection locations to reduce local irritation Inject slowly and wait briefly before removing needle Track daily dosing and site rotation for consistency Human clinical evidence remains limited

ACKNOWLEDGMENTS JV, BV, DM, and MS performed the surgery and conducted the assessments