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Heres the whole thing in plain terms: What they did: built and validated a lab-grade method to accurately measure 5A1MQ in the blood, then dosed rats two ways intravenous (IV) and oral and tracked exactly how much showed up in circulation over time

Commonly referenced guidance includes: Initial replacement Maintenance For maintenance, the BNF lists adult prophylaxis/maintenance dosing such as 1 mg intramuscularly every 23 months in appropriate cases
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Unlike medical doctors, they do not attend conventional medical school
