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Conclusions Targeted metabolomics demonstrated that aspirin treatment and hypoxic stimulation additively upregulated intracellular glutamine levels in PIK3CA -MT colorectal cancer cells
If glutathione constitutes a glutamate reservoir, then inhibiting GGT with acivicin should lead to decreased cellular glutamate, as this enzyme is upstream of the ultimate liberation of glutamate from the cycle (Fig
Non-obese Humans Cell Metab
Targeting Bromodomain-Selective Inhibitors of BET Proteins in Drug Discovery and Development
