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In terms of iron metabolism and homeostasis in immune cells, a study revealed that iron overload promotes abnormal differentiation of pathogenic T cells, including follicular helper T cells, by regulating DNA demethylation, thus exacerbating autoantibody production and the development of systemic lupus erythematosus (SLE) [26]
Martin Gerdes, Yibo Wang Circulation Research.2025
Safety facets and issues related to nanotechnological approaches As there is a remarkable use of nano-tailored drug delivery, the main concern is their safety
10.1021/acschembio.2c00317 ACS Chem
