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Description
Men generally have stronger central nervous system modulating elements for dampening pain signals
The intestinal barrier may, therefore, be a target for therapeutic approaches to alter the course and mitigate the complications associated with a disruption in its functions
Factors That Make Side Effects Last Longer Or Become More Severe Faster dose escalation increases early GI symptoms
10.1186/s12929-017-0385-1 63 SakuraiT.HeG.MatsuzawaA.YuG.-Y.MaedaS.HardimanG.et al (2008)
