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494 This disruption results in a less stable knee joint at the moment of ground contact, increasing the risk of valgus collapse or anterior tibial translation, which are common mechanisms of ACL injury

Finally, the authors observed that p-JNK and p-38 levels were reduced in 3-HAA-treated DC2.4 cells and bone marrow-derived DCs

In vivo experiments revealed that EDT inhibited tumor growth, exacerbated mitochondrial dysfunction, and decreased Nrf2 expression in mouse tumor tissues

More work is needed to put these findings into a physiologic framework and explore their potential for cancer therapy and beyond
