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Since no appropriate PR3-AAV model exists, clinical studies with adjunctive DPP1 inhibitor administration in patients with PR3-AAV may provide the best approach to test this hypothesis

Information from field studies should be further exploited to assess how these variables affect viral persistence, enabling the design of biosecurity measures tailored to local climatic and ecological circumstances

Nonetheless, two IV studies have been published related to Parkinsons disease, one open-label which found significant improvement and a slowing of the disease, and one randomized and double-blinded which found only mild symptomatic improvement