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Davis JL, Paris HL, Beals JW, Binns SE, Giordano GR, Scalzo RL, Schweder MM, Blair E, Bell C (2016) Liposomal-encapsulated ascorbic acid: influence on vitamin C bioavailability and capacity to protect against Ischemia-Reperfusion Injury

In brief, when TrkB and p75 NTR co-express in the same cells, p75 NTR enhances neurotrophin binding to TrkB, augmenting both ligand affinity and selectivity, hence, reinforcing the TrkB-mediated trophic response via up-regulation of PI3K/Akt and/or IRAK/NF-B signaling 3
A natural compound revitalizes the aging human immune system

doi: 10.1210/jc.2018-02202 192 BeccutiGGuaraldiFNattaGCambriaVPrencipeNCicolinAet al
