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The oxidative stress index (OSI) was calculated using the following formula: The spectrophotometric measurement of paraoxonase (PON-1) activity was performed using a commercial PON-1 assay kit (RelAssay Diagnostics, Gaziantep, Turkey)

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Blood work every 6 weeks during the first 12 weeks, then every 8 to 12 weeks thereafter, is the only way to know whether your symptoms reflect an optimal dose or a dose requiring adjustment
