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The impact of dihydromethysticin on the formation of NNK-induced lung adenomas and adenocarcinomas in A/J mice has been reported

Peptide therapies may offer targeted approaches for gut repair and immune modulation, though more clinical research is needed to confirm long-term effectiveness

Data availability Additional data are made available in supplementary tables of this manuscript

The ANLS hypothesis proposes a coherent model where glutamate uptake by astrocytes stimulates their glycolysis, leading to lactate production and export, which is then taken up and oxidatively metabolized by neurons to meet activity-dependent energy demands (Brooks, 2018
