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Molecular mechanisms regulating NPPCs in IDD Under conditions of elevated oxidative stress, excessive reactive oxygen species (ROS) accumulation and mitochondrial damage activate senescence pathways like P53/P21, contributing to accelerated ECM catabolism and NPPC senescence [76]

iScience 2020, 23, 101005

Improved energy balance regulation pathways

(12) D Philp, M Nguyen, B Scheremeta, et al (2004) Thymosin beta4 increases hair growth by activation of hair follicle stem cells FASEB Journal, 2004 Feb, Volume 18 (Issue 2), Pages 385-7
