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Further investigation showed that CPs first reduce the level of skin oxidation, inhibit the expression of the key transcription factor AP-1 (c-Jun and c-Fos), then activate the TGF-/Smad signaling pathway to promote collagen synthesis, inhibit the expression of MMP-1/3 to inhibit collagen degradation, and inhibit skin inflammation to alleviate skin aging in mice

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Harvison PJ, Guengerich FP, Rashed MS, Nelson SD: Cytochrome P450 isozyme selectivity in the oxidation of acetaminophen

Evidence-Based Recommendations for Safe Glutathione Use Clinical research provides valuable guidance for safe and effective glutathione supplementation practices