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142 : 8088 Marcus DL, de Leon MJ, Goldman J, Logan J, Christman DR, Wolf AP et al

Aerobic exercise potently activates AMPK, enhancing mitochondrial biogenesis, fatty acid oxidation, and glucose uptake via GLUT4 translocation, thereby ameliorating systemic IR and reducing ectopic lipid deposition (142146)

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ACTH-Dependent Cushings Syndrome add Most cases of naturally occurring Cushings syndrome (80-85%) (Melian et al, 2010) are caused by hypersecretion of ACTH by a lesion in the pituitary gland (typically pituitary neoplasia or hyperplasia)